Covers core aspects of cancer pathology, treatment, epidemiology, the discovery of oncogenes and tumor suppressors, and the molecular genetics underlying the characteristic features of malignant tumors (including metastatic behavior, genomic instability, angiogenesis, cell cycle regulation, and apoptosis). Strong emphasis on the biochemical functions of cancer-related proteins and enzymes and therapeutic approaches based on our understanding of these proteins. Important experimental approaches that have influenced our current understanding of cancer will also be stressed. Three lecture hours a week for one semester. Prerequisite: Biology 325 or 325H with a grade of at least C-; and one of the following with a grade of at least C-: Biochemistry 339F, 369, Biology 330, 360K.