Introduction to major biomedical imaging modalities, including X-ray radiography, computed tomography (CT), nuclear medicine (SPECT and PET), magnetic resonance imaging (MRI), and ultrasound. Emphasis on principles, approaches, and applications of each imaging modality. Basic physics and imaging equations of the imaging system; hardware and software; sources of noise and primary artifacts; safety and patient risk. Three lecture hours and two laboratory hours a week for one semester.