Broad issues of molecular pharmacotherapeutics, including potential and challenge for optimization of drug therapy, implications for drug development and regulation, ethical and social aspects of pharmacogenomics, signal transduction, use of knock-out mice, and informed consent process in pharmacogenomic research. Three lecture hours a week for one semester. Pharmacy 381W and Pharmacy Graduate Studies 381W may not both be counted. Offered on the letter-grade basis only. Prerequisite: Graduate standing and consent of instructor.