Microorganisms in chemical and biochemical synthesis; genetic manipulation of cells by classical and recombinant DNA techniques. Enzyme technology; design of bioreactors and microbial fermentations; separations of biological products. Three lecture hours a week for one semester. Only one of the following may be counted: Biology 335, Biomedical Engineering 339, Chemical Engineering 339, 379 (Topic: Introduction to Biochemical Engineering). Prerequisite: Biochemistry 339F or 369, and Biology 311C with a grade of at least C-.