Computational image processing, computational geometry and geometric modeling algorithms with an emphasis on spatial realism, and the programmatic use of physiological simulation and visualization to quantitatively depict how things work at the molecular, cellular, tissue, organ, and system levels. Three lecture hours a week for one semester. Computer Science 384R and 395T (Topic: Graphics, Modeling, and Visualization) may not both be counted; Computer Science 384R and 395T (Topic: Multiscale Bio-Modeling and Visualization) may not both be counted; Computer Science 384R and 395T (Topic: Physically Based Geometric Modeling) may not both be counted. Prerequisite: Graduate standing, and Computer Science 354 or consent of instructor.