Discuss core aspects of cancer pathology, treatment, epidemiology, the discovery of oncogenes and tumor suppressors, and the molecular genetics underlying the characteristic features of malignant tumors (including metastatic behavior, genomic instability, angiogenesis, cell cycle regulation, and apoptosis). Examine the biochemical functions of cancer-related proteins and enzymes and therapeutic approaches based on our understanding of these proteins. Explore important experimental approaches that have influenced our current understanding of cancer. Three lecture hours a week for one semester. Biology 336 and Molecular Biosciences 336 may not both be counted. Prerequisite: Biology 325 or 325H with a grade of at least C-; and one of the following with a grade of at least C-: Biochemistry 339F, Biochemistry 369, Molecular Biosciences 330 (or Biology 330), or Molecular Biosciences 360K (or Biology 360K).