BME 346 BME 346. Computational Biomolecular Engineering. 3 Hours.
Restricted to biomedical engineering majors. Introduction to computational structural biology and molecular modeling, including the fundamentals of biomolecular structure and molecular thermodynamics. The principles and applications of biomolecular modeling used to explore the critical relationship between structure, function, and thermodynamic driving forces in molecular biology. Three lecture hours a week for one semester. Prerequisite: The following coursework with a grade of at least C-: Biochemistry 369, Biology 311C or 315H, Biomedical Engineering 313L or Computational Engineering 311K, and one of the following: Biomedical Engineering 355, Chemistry 353 or 353M.
The mission of the Department of Biomedical Engineering is to develop clinically translatable solutions for human health by training the next generation of biomedical engineers, cultivating leaders, and nurturing the integration of science, engineering, and medicine in a discovery-centered environment. The main educational objective is to provide a thorough training in the fundamentals of engineering science, design, and biology. The curriculum is designed to provide concepts central to understanding living systems from the molecular and cellular levels to the tissue and organismal levels. The curriculum incorporates principles of vertical integration, leading to the choice of a technical area (biomedical imaging and instrumentation, cellular and biomolecular engineering, computational biomedical engineering, or molecular, cellular, and tissue biomechanics), and culminates in a team capstone design experience. Students are expected to develop an understanding of industrial, research, and clinical biomedical engineering environments; an understanding of regulatory issues and biomedical ethics; the ability to create, identify, formulate, and solve biomedical engineering problems; the ability to design systems to meet needs in medical/life science applications; an understanding of life processes at the molecular, cellular, tissue, and organismal levels; the ability to use instrumentation and to make measurements and interpret data in living systems; and an appreciation of the interdisciplinary nature of biomedical engineering research.